Biology Scientist I–III (Assay)
Shanghai R&D1.Development of molecular interaction assay methods: Primarily responsible for developing, optimizing, and validating analytical methods for assessing molecular affinity, binding kinetics, and protein expression levels, with a technical focus on HTRF (Homogeneous Time-Resolved Fluorescence), FP (Fluorescence Polarization), and BLI (Bio-Layer Interferometry). Perform cell-based assays to comprehensively evaluate the cell binding, internalization, and intracellular trafficking of antibodies and peptides from the delivery platform.
2.Routine sample testing and data analysis: Undertake routine testing of various samples across projects, performing high-quality experiments including HTRF, FP, BLI, ELISA, FACS, and Incucyte assays. Process, analyze, and interpret raw data in a professional manner.
3.Instrument management and report writing: Operate, maintain, and troubleshoot precision instruments (e.g., multimode plate readers, Octet systems, etc.). Independently complete data analysis and draft experimental reports for assigned tasks, ensuring result reliability and traceability.
4.Other responsibilities: Stay informed about emerging technologies and novel methodologies in the field and provide constructive recommendations to supervisors. Complete other related tasks assigned by management.
1.Bachelor's or Master's degree in Biochemistry, Pharmacology, Biophysics, or related disciplines.
2.In-depth understanding of the principles of protein-protein and protein-small molecule interactions.
3.Extensive hands-on experience with ELISA, FACS, and related techniques.
4.Proficiency in at least one molecular interaction analysis technology among HTRF, FP, BLI, and SPR, with demonstrated experience in independently designing and executing relevant experiments.
5.Strong data analysis capabilities, with proficiency in professional software such as GraphPad Prism.
6.Clear logical thinking, strong learning ability, and a genuine passion for exploring new technologies.
In Vivo Scientist (CNS)
Shanghai R&D1.Mouse/rat dosing and sample collection. Efficiently perform in vivo drug administration via routes including ICV, IV, and IT; collect blood, cerebrospinal fluid (CSF), and CNS tissues as required; reasonably schedule and carefully execute experiments according to project plans; and complete experimental records and project reports in accordance with company policies.
2.CNS model establishment and behavioral testing. Establish CNS disease models and perform behavioral tests following existing SOPs; develop new CNS models and behavioral testing methods as project needs arise; reasonably schedule and carefully execute experiments according to project plans; and complete experimental records and project reports in a timely manner.
3.Maintain standardized experimental documentation. Keep complete and accurate experimental records; promptly summarize work and submit experimental data as required; timely report experimental results; and write daily reports and study completion reports.
4.Laboratory consumables inventory management. Track and report laboratory consumable usage in a timely manner; responsible for submitting purchase requisitions, procuring consumables, and managing inventory inflow/outflow.
5.Compliance with all regulations. Familiarize with and adhere to all company policies and regulations; complete other tasks assigned by supervisors.
1.Educational background: Bachelor's degree or above in Neurobiology or related disciplines.
2.Required work experience: For bachelor's degree holders, at least 3 years of experience in in vivo drug administration (neural tissue) in animals, with hands-on experience in intrathecal (IT) and/or intracerebroventricular (ICV) injections; a neurobiology-related background and a willingness to work with laboratory animals are essential.
3.Essential skills and attributes: Proficiency in mouse/rat stereotaxic intracranial injection, tail vein injection, subcutaneous injection, and intrathecal injection; experience in collecting neural tissues from mice/rats; competence in establishing neurological animal models and performing behavioral tests; rigorous and responsible work ethic with complete and accurate experimental records and reports; good communication and learning abilities; strong team collaboration spirit; diligent, hardworking, and highly responsible.
In vitro Group Head
Shanghai R&D1.Leadership & Team Management:Lead and manage a team of 10+ scientists focused on in vitro assay development;Build a high-performing, collaborative, and accountable team culture;Define priorities, allocate resources, and ensure timely delivery across multiple programs;Recruit, mentor, and develop scientific talent
2.In Vitro Assay Development
• Oversee design, development, optimization, and validation of:Cell-based assays (mechanism of action, potency, functional readouts);Biochemical and biophysical assays (binding, kinetics, affinity characterization);Ligand binding assays (target engagement, ligand interactions);PD biomarker assays ;PK-related in vitro assays
• Establish assay systems to support:Target identification and validation;Lead candidate screening and optimization;Mechanistic understanding of siRNA therapeutic
3.Platform & Portfolio Support:Support company-wide discovery and preclinical programs across CNS and non-CNS indications;Contribute to development and scaling of platform assay capabilities for oligonucleotide therapeutics;Enable data generation to inform candidate selection and advancement decision
4.Cross-functional Collaboration:Partner closely with:Biology and disease area teams;Delivery platform teams;Oligonucleotide chemistry and platform teams;Translational and clinical teams;Effectively communicate data, insights, and strategy to internal stakeholders and senior leadership
5.Operational Excellence:Establish and implement fit-for-purpose assay validation standards and SOPs;Ensure data quality, reproducibility, and scientific rigor;Manage external collaborations (e.g., CROs) as needed
6.Complete the other tasks assigned by the superior.
1.Ph.D. in Molecular Biology, Pharmacology, Biochemistry, Neuroscience, or related field
2.5+ years of industry experience in drug discovery/development
3.Prior experience leading assay development teams in a biotech or pharmaceutical setting
Technical Expertise
4.Strong background in:In vitro assay development and validation;Cell-based and biochemical assay platforms;PK/PD and biomarker assay development;Oligonucleotide therapeutics (siRNA/ASO) preferred
5.Experience with technologies such as:Protein quantification (e.g., ELISA, MSD, Western blot);Binding and biophysical assays;Flowcytometry
6.Leadership & Competencies:Demonstrated ability to lead and scale high-performing scientific teams;Strong project management skills with focus on execution and timelines;Excellent communication and cross-functional collaboration skills;Ability to operate effectively in a fast-paced, dynamic environment;Highly motivated, hands-on leader with strong problem-solving capabilities
Antibody Scientist (AOC Purification)
Shanghai R&D1.AOC preparation tasks, including but not limited to antibody processing, antibody conjugation and purification, material preparation, sample aliquoting, storage and inventory management, SDS-PAGE or SEC characterization of samples, and instrument maintenance.
2.Laboratory management: participate in routine laboratory housekeeping duties on a rotational basis.
3.Participate in the characterization and analytical testing of AOC products, including but not limited to BLI affinity measurements, endotoxin testing, HPLC, LC-MS analysis, etc.
4.Maintain key equipment such as the AKTA system and perform routine calibrations.
5.Participate in project progress reporting and discussions.
6.Complete other tasks assigned by supervisors.
1.Bachelor's degree or above, with at least 2 years of relevant experience in protein purification.
2.Familiar with protein purification workflows and principles, and knowledgeable about commonly used purification equipment and instruments.
3.Strong sense of responsibility, proactive work ethic, and good team collaboration skills.
Antibody Scientist (Fermentation)
Shanghai R&D1.Proficient in CHO cell suspension culture techniques, including cryopreservation, thawing, passaging, expansion, and aseptic manipulation.
2.Responsible for the daily operation and maintenance of 1–3 L mammalian cell bioreactors, including pre-fermentation equipment calibration and parameter setup, real-time monitoring and precise regulation of key parameters (temperature, pH, dissolved oxygen, agitation speed, etc.) during the fermentation process, to ensure stable mammalian cell culture operations.
3.Responsible for the cleaning, sterilization, and management of fermentation-related laboratory equipment and utensils; strictly enforce laboratory biosafety and hygiene protocols to prevent cross-contamination and ensure a safe experimental environment and operational safety.
4.Assist in the preparation of fermentation-related technical documentation, including fermentation process records, equipment SOPs, experimental reports, and collaborate with the team on the compilation and archiving of technical outputs.
5.Cooperate with the team to complete other related R&D or production support tasks, including CHO cell transient transfection, stable cell line construction, antibody purification, and analytical testing, to ensure smooth project progress.
1.Bachelor's degree or above in Biology, Pharmacy, or related fields.
2.At least 2 years of experience in mammalian cell fermentation, with familiarity in mammalian cell culture, inoculation, fermentation workflows, and proficiency in using Applikon bioreactors.
3.Ability to independently troubleshoot technical issues arising during fermentation; familiar with fermentation processes and batch production management.
4.Experience in CHO cell transient transfection, stable cell line construction, antibody purification, and analytical testing is highly preferred.
5.Good communication skills, strong sense of responsibility, patience and attention to detail, with a strong willingness to learn and a collaborative team spirit.
China Business Development Director
Shanghai BD&Strategy1.Contribute to and implement the China and Asia-Pacific business development strategy to support the company’s long-term objectives.
2.Identify, evaluate, and pursue strategic opportunities consistent with Argo’s near-term and long-term growth objectives across the continuum of partnership structures in the region.
3.Lead end-to-end deal execution, including interfacing externally, aligning with internal stakeholders, and executing all stages of partnership processes.
4.Build and maintain strong relationships with key stakeholders, including domestic and international biotech and pharmaceutical companies, academic institutions, investors, and industry partners.
5.Collaborate closely with internal teams, including R&D, Clinical, Finance, and Alliance, to ensure alignment and successful integration of partnerships.
6.Monitor market trends, competitive landscape, and emerging opportunities in China and Asia-Pacific to inform strategic decision-making.
7.Represent the company at industry conferences, networking events, and partner meetings to enhance visibility and foster new relationships with a focus on the region.
8.Prepare and present business cases, recommendations, and progress updates to senior leadership, including the CBO and executive team.
1.Ph.D., M.D., Pharm.D., MBA, or advanced degree in Life Sciences, Biotechnology, Medicine, Pharmacy, Business, or a related discipline preferred.
2.8+ years of experience in biotechnology, pharmaceutical, healthcare consulting, investment, corporate strategy, or business development.
3.Demonstrated experience supporting or leading strategic transactions, including licensing, partnerships, collaborations, M&A evaluation, or corporate development initiatives.
4.Exposure to transaction execution processes, including opportunity assessment, due diligence, valuation, negotiation, and deal structuring.
5.Prior experience in consulting, investment banking, venture capital, corporate strategy, or business development within innovative biopharmaceutical companies is highly preferred.
Technical & Business Competencies
6.Strong scientific and medical understanding across drug discovery, development, regulatory, and commercialization processes.
7.Ability to assess asset value, commercial opportunity, competitive positioning, and strategic fit.
8.Strong business acumen with the ability to translate scientific innovation into compelling business narratives for internal and external stakeholders.
9.Experience preparing executive-level analyses, business cases, and recommendations for senior management, investors, and Board members.
10.Excellent project management skills with demonstrated ability to manage multiple complex initiatives simultaneously.
11.Exceptional communication and stakeholder management skills, with the ability to engage effectively across global cross-functional teams.
12.Strong executive presence and experience interacting with senior leadership, Board members, investors, and strategic partners.
13.Proven ability to influence decision-making and drive alignment among diverse stakeholders.
14.Fluent in Mandarin and English, with strong written and verbal communication skills in both languages.
Portfolio Strategy AD/D (US)
USA Management1. Supervise and manage the company's pipeline and projects under development to ensure that their progress aligns with the company's strategic goals.
2. Develop and implement pipeline and project management methods, processes, and practices, and continuously optimize them.
3. Coordinate the allocation of project resources across all relevant departments such as Research Department, CMC, QA, Preclinical Department, and Clinical Development Department, manage the financial and material resources required for the project, including budget preparation and cost control, optimize resource allocation, and improve resource utilization efficiency.
4. Develop project plan, monitor project progress, and regularly update project status.
5. Manage project timelines effectively, ensure the reasonable setting and strict adherence to key project milestones, coordinate cross departmental cooperation, accelerate research and development speed, avoid project delays, and adjust project schedules as necessary to address unforeseen challenges.
6. Identify potential risks in the project and develop a risk mitigation plan. Monitor risk factors and take timely measures to reduce the impact on the project
7. Ensure project management complies with industry standards, law, regulatory requirements, and company internal control policies
8. Communicate effectively with cross departmental teams to effectively advance project progress, and regularly report project status and performance to senior management and stakeholders. 9.Complete other tasks assigned by superiors.
1. Bachelor's degree or above, in life sciences, pharmacy, clinical or chemistry, etc.
2. Familiar with and full knowledgeable in the relevant regulations of clinical trials and GCP and other applicable guidelines.
3. At least 5 years of experience in innovative drug management and project management, with at least one complete project management practice from IND to NDA
Accounts Payable Manager / AM
Shanghai Management1.Review supplier payment requests and expense reimbursement documents to ensure compliance with company policies and relevant fiscal and tax regulations.
2.Complete month-end journal entries for expense-related payments on a timely basis.
3.Address process-related issues for expense payments in the OA system and follow up on subsequent system optimization efforts.
4.Follow up on issue resolution related to OA-ERP integration.
5.Coordinate employee training on expense reimbursement and payment application procedures.
6.Conduct regular reconciliations with suppliers, including updating financial subsidiary ledgers (prepayments and payables), following up on the clearance of long-outstanding prepayments without received invoices, and verifying balances with suppliers.
7.Follow up on the filing of R&D-related contracts and related-party transaction contracts.
8.Complete other tasks assigned by supervisors.
1.Bachelor's degree or above in Finance, Economics, Management, or related disciplines.
2.At least 8 years of experience in finance/accounting-related roles; experience in the biopharmaceutical industry is preferred.
3.Proficient in various office software applications, such as PPT and Excel.
4.Solid professional knowledge in finance and accounting, familiar with financial management, enterprise accounting standards, cost and expense management, and related competencies.
5.Strong organizational and coordination skills, with the ability to establish and maintain effective working relationships across departments.
6.Proactive, resilient, able to work under pressure, and possess strong execution and follow-through capabilities.
Clinical Pharmacology Analysis Senior Manager / AD
Shanghai Clinical Development1.Integrate and analyze preclinical efficacy, DMPK, and toxicology data; conduct comprehensive research on clinical pharmacology data for similar targets in the same class, and collaborate with the clinical team.
2.Assist in the design of clinical pharmacology study protocols, and be responsible for the interpretation and organization of PK and PK/PD data.
3.Perform PK/PD modeling and popPK/PD analysis; integrate preclinical and clinical data to predict in vivo efficacy responses and dose-exposure-response relationships in humans.
4.Conduct systematic literature reviews, track and integrate cutting-edge modeling methodologies (e.g., siRNA delivery mechanisms, target-mediated drug disposition models, etc.), and optimize internal modeling strategies.
5.Prepare relevant materials during the clinical study initiation phase, including competitive product intelligence research, model-based analysis summaries, and justification for primary endpoint selection.
6.Support the review and drafting of clinical pharmacology-related sections in documents such as the Investigator's Brochure (IB) and study protocols.
7.Assist in drafting clinical pharmacology-related content for clinical development plans, clinical trial protocols, IND and NDA submission dossiers, etc.
8.Collaborate with clinical, bioanalytical, and preclinical teams to explore correlations between biomarkers and clinical endpoints, and support subsequent model development.
9.Participate in biomarker selection, validation protocol design, and interpretation of results.
10.onduct competitive landscape analysis and regulatory policy interpretation.
11.Comply with all established policies and regulations, and complete other tasks assigned by supervisors.
1.Ph.D. in Pharmacy, Pharmacology, Bioengineering, Computational Biology, or related fields with at least 3 years of experience; or Master's degree with significant industry experience (5+ years).
2.Minimum 5 years of experience in population PK/PD modeling, with proficiency in tools such as NONMEM, Phoenix, R/Python, etc.
3.Full-cycle participation in at least one innovative drug clinical development program (Phase I–III), with a solid understanding of regulatory requirements (FDA/EMA).
Medical Writing (Sr.) Manager
Shanghai Clinical Development1.Responsible for editing and drafting clinical study-related documents in both Chinese and English, including clinical study protocols, investigator brochures, informed consent forms, clinical study reports, interim analysis reports, drug safety update reports, etc., ensuring their scientific accuracy and regulatory compliance.
2.Medical support and cross-functional collaboration, including close cooperation among project manager, clinical research physician, data management, statisticians, and pharmacovigilance specialists. Familiar with clinical study procedures, GCP, ICH guidelines, and other regulations.
3.Rearch, translate, and organize domestic and international medical literature, industry guidelines, and the latest research progress to provide evidence support for document drafting. Simultaneously, monitor changes in regulatory policies to ensure that the content of clinical trial-related documents meets applicable regulatory requirements.
4.Participate in the quality control of clinical study-related documents, review translated documents, and ensure that document format, terminology, and content comply with standard operating procedures and regulatory requirements.
5.Participate in the writing of medical journal or conference papers and materials (such as abstracts, posters, presentation slides), manuscript, product label, and the patient education materials or training materials.
6.Complete other tasks assigned by superiors.
1.Master's degree or above in medicine, pharmacy/nursing or other life sciences, candidates with clinical medicine background is preferred 2.3-5 years of relevant work experience in pharmaceutical companies; with experience in MNC is preferred.
3.Familiar with clinical study procedures, GCP, ICH guidelines, and other regulations.
4.Possess literature retrieval and review capabilities
5.Proficient in common office software, such as Word, Excel, PowerPoint, and Outlook.
6.With strong communication and coordination skills.
7.Excellent English reading and writing skills, and strong English communication skills
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